| | dblpen | | Double Penetration |
| | DBLS | | double room with shower |
| | DBLT | | Dynamic Back Link Technology |
| | DBM | | Divorced Black Male |
| | DBMS | | DataBase Management System |
| | DBN | | Doing Business, NOT |
| | DBNR | | Dictated But Not Read |
| | DBNR | | Differenced Normalized Burn Ratio |
| | DBSS | | Don't Be So Stupid |
| | DCC | | Direct Computer Connection |
| | DCE | | Distributed Computing Environment |
| | DCMAT | | Do Call Me Any Time |
| | DCMICY | | Don't Call Me, I'll Call You |
| | DCOM | | distributed component object model |
| | DCOSM | | Don't cry over spilt milk |
| | DCYCBTAH | | Don't count your chickens before they are hatched |
| | DCYCBTH | | Don't Count Your Chickens Before They're Hatched |
| | DDCD | | Double Density CD |
| | DDD | | Direct Distance Dial |
| | DDDK | | Device Driver Development Kit |
| | dde | | doesn't do extras |
| | dde | | Doesn’t do extras |
| | dde | | dynamic object embedding |
| | DDF | | Drug and Disease Free |
| | DDG | | drop dead gorgeous |
| | DDL | | Data Definition Language |
| | DDL | | direct download |
| | DDR | | Dance Dance Revolution |
| | DDR | | Double Data Rate |
| | DDR | | Dual Data Rate |
|