| | E-OTD | | Enhanced Observed Time Difference |
| | e.c.e.g. | | easy come, easy go |
| | E.D.G.E. | | Enhanced Data for GSM Evolution |
| | E.F.N.I. | | Earth Force Naval Intelligence |
| | E.G.A.D. | | Everyone's Got a Dream |
| | E.O.E. | | Equal Opportunity Employer |
| | E.O.F.Y. | | End of Financial Year |
| | E.P.O.S. | | Electrical Point of Sale |
| | e.t.a. | | estimated time of arrival |
| | E.T.D. | | estimated time of departure |
| | E.T.L. | | extraction, transformation, and load |
| | eacu | | emergency acute care unit |
| | EAEC | | East Asia Economic Caucus |
| | EAEC | | East Asiatic Economic Council |
| | EAEC | | European Atomic Energy Community |
| | eai | | enterprise application integration |
| | EAK | | Eating At Keyboard |
| | EAMAUL | | Eat As Much As You Like |
| | EAMAYL | | Eat As Much As You Like |
| | EAP | | economically active population |
| | EAP | | Employee Assistance Program |
| | EAP | | Extensible Authentication Protocol |
| | EASDAQ | | European Association of Securities Dealers Automated Quotation |
| | EAV | | Entity Attribute Value |
| | EAWWT | | Even A Worm Will Turn |
| | ebbak | | Error Between Brain and Keyboard |
| | EBE | | Extraterrestrial Biological Entity |
| | EBIT | | earnings before interest and taxes |
| | EBITDA | | Earnings Before Interest, Taxes, Depreciation |
| | EBITDA | | earnings before interest, taxes, depreciation and amortization |
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