| | HCB | | Holy Cow, Batman! |
| | HCIERY | | How Can I Ever Repay You |
| | HCIT | | How cool is that |
| | HCIT | | How Cute is That |
| | HCM | | Human Capital Management |
| | HCN | | Hydrogen Cyanide |
| | hcrp | | hardcopy cable replacement profile |
| | HCV | | Hepatitis C virus |
| | HDCD | | High Definition Compact Digital |
| | HDCD | | High Definition Compatible Digital |
| | HDGI | | He Doesn't Get It |
| | HDMI | | high definition multimedia interface |
| | HDML | | Handheld Device Markup Language |
| | HDRI | | high dynamic range image |
| | HDTV | | High Definition Television |
| | HDTV | | high-definition digital television |
| | HDYLTDTTWYLOTBOMNAWCYDIA | | How did you learn to do that thing with your lips on the back of my neck and when can you do it again |
| | HDYLTDTTWYLOTBOMNAWCYDIA? | | How did you learn to do that thing with your lips on the back of my neck and when can you do it again? |
| | HEPA | | High Efficiency Particulate Air |
| | HEPA | | High Efficiency Particulate Arrestance |
| | HF | | have fun |
| | HFC | | Haven't a f**king Clue |
| | HFIL | | Home For Infinite Losers |
| | HFS | | Hierarchical File System |
| | HFS | | holy f**king sh*t |
| | HFS | | holy f**king sh*t |
| | HFT | | Hands Free Telephone |
| | HFTROYL | | Have fun for the rest of you life |
| | HFUY | | here for you why? |
| | HGV | | Heavy Goods Vehicle |
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