| | sfyl | | swim for your life |
| | SG&A | | Selling, General, and Administrative |
| | SGFIT | | Search Google For It |
| | SGML | | Standardised Generalised Markup Language |
| | SGML | | Standardized General Markup Language |
| | sha | | secure hash algorithm |
| | shmily | | see how much I love you |
| | shmily | | showing how much i love you |
| | SHTML | | Static Hypertext Mark-up Language |
| | sibir | | sibling in room |
| | simm | | single inline memory module |
| | simm | | system in-line memory modules |
| | SIMMs | | Single Inline Memory Modules |
| | SINK | | Single Income No Kids |
| | SINK | | Single Income, No Kids |
| | siop | | Single Integrated Operational Plan |
| | sis,sig | | speech is silver, silence is golden |
| | SIT | | socially interactive technologies |
| | SIT | | stay in touch |
| | SITC | | single in the city |
| | sitrep | | situation report |
| | SITW | | State Income Tax Withholding |
| | SJF | | Single Jewish Female |
| | SJM | | Single Jewish Male |
| | SKOTC | | Soft kiss on the cheek |
| | sku | | Stock Keeping Unit |
| | SLBM | | Submarine-Launched Ballistic Missile |
| | SLC | | Single level cell |
| | slcds | | Spring-Loaded Camming Devices |
| | SLD | | Second level domain |
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